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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMF1 All Species: 22.12
Human Site: T248 Identified Species: 30.42
UniProt: P82094 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P82094 NP_009045.2 1093 122842 T248 T P S P P V S T F S S G T S T
Chimpanzee Pan troglodytes XP_526227 1093 122795 T248 T P S P P V S T F S S G T S T
Rhesus Macaque Macaca mulatta XP_001088711 1092 122828 T247 T P S P P V S T F S S G T S T
Dog Lupus familis XP_533766 1089 122761 S246 S P P I S T F S S G T S T T S
Cat Felis silvestris
Mouse Mus musculus B9EKI3 1091 121796 S246 S P P V S S F S S G T S T T S
Rat Rattus norvegicus NP_446123 1093 121882 S247 S P P V S S F S S G T S T T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510334 1106 124384 T254 T P S P P I S T F S S G T S T
Chicken Gallus gallus O42184 1433 161009 R346 E T S S R Y A R K I S G T T A
Frog Xenopus laevis Q5PQ23 649 75475
Zebra Danio Brachydanio rerio NP_001003522 1136 126986 A274 T P S P P V S A F S S G T S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572360 933 103794 L198 S T K T M K A L V L S D I Q V
Honey Bee Apis mellifera XP_394037 1326 150590 S287 C S V S N L A S P A T G T K V
Nematode Worm Caenorhab. elegans P02566 1966 225108 E879 E D S L A K E E K L R K E L E
Sea Urchin Strong. purpuratus XP_785821 1176 131318 N253 K S E D S A I N P E N V K S T
Poplar Tree Populus trichocarpa XP_002303293 975 109171 P241 E V S N E P Q P E A L N D V Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WVL7 956 108335 P222 N K D T V H S P V L D G Q H K
Baker's Yeast Sacchar. cerevisiae P47166 707 81153
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.5 93.1 N.A. 87.2 86.7 N.A. 81.2 21.7 22.6 59.7 N.A. 26.1 23.9 21 37.7
Protein Similarity: 100 99.4 99.1 96.1 N.A. 92.5 92 N.A. 88.3 39.9 37.3 74.6 N.A. 45.8 44.9 36.6 56.8
P-Site Identity: 100 100 100 13.3 N.A. 13.3 13.3 N.A. 93.3 26.6 0 93.3 N.A. 6.6 13.3 6.6 13.3
P-Site Similarity: 100 100 100 46.6 N.A. 46.6 46.6 N.A. 100 40 0 93.3 N.A. 20 46.6 6.6 20
Percent
Protein Identity: 25.8 N.A. N.A. 27.1 21.1 N.A.
Protein Similarity: 47.2 N.A. N.A. 45.4 39.4 N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 0 N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 6 6 18 6 0 12 0 0 0 0 6 % A
% Cys: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 6 6 6 0 0 0 0 0 0 6 6 6 0 0 % D
% Glu: 18 0 6 0 6 0 6 6 6 6 0 0 6 0 6 % E
% Phe: 0 0 0 0 0 0 18 0 30 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 18 0 48 0 0 0 % G
% His: 0 0 0 0 0 6 0 0 0 0 0 0 0 6 0 % H
% Ile: 0 0 0 6 0 6 6 0 0 6 0 0 6 0 0 % I
% Lys: 6 6 6 0 0 12 0 0 12 0 0 6 6 6 6 % K
% Leu: 0 0 0 6 0 6 0 6 0 18 6 0 0 6 0 % L
% Met: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 6 0 0 6 6 0 0 6 0 0 6 6 0 0 0 % N
% Pro: 0 48 18 30 30 6 0 12 12 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 6 0 0 0 0 0 6 6 6 % Q
% Arg: 0 0 0 0 6 0 0 6 0 0 6 0 0 0 0 % R
% Ser: 24 12 48 12 24 12 36 24 18 30 42 18 0 36 18 % S
% Thr: 30 12 0 12 0 6 0 24 0 0 24 0 59 24 36 % T
% Val: 0 6 6 12 6 24 0 0 12 0 0 6 0 6 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _